产品详情 |
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Antigenic Specificity | Fentanyl |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | n/a |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | ELISA: 2.5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Fentanyl Polyclonal Antibody. Fentanyl is a synthetic, lipophilic phenylpiperidine opioid agonist with analgesic and anesthetic properties. Fentanyl selectively binds to the mu-receptor in the central nervous system (CNS) thereby mimicking the effects of endogenous opiates. Stimulation of the mu-subtype opioid receptor stimulates the exchange of GTP for GDP on the G-protein complex and subsequently inhibits adenylate cyclase. This results in a decrease in intracellular cAMP and leads to a reduction in the release of neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline. The analgesic effect of fentanyl is likely due to its metabolite morphine, which induces opening of G-protein-coupled inwardly rectifying po |
Immunogen | n/a |
Other Names | C22H28N2O; Fentanil; Duragesic; Fentanest; Phentanyl |
Gene, Accession # | n/a |
Catalog # | PA1-75146 |
Price | |
Order / More Info | Fentanyl Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
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