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| Product Name | Recombinant Human Secreted Ly-6/uPAR domain-containing protein 2 (SLURP2) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 10kDa. Full Length of Mature Protein: 23-97aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Binds and may modulate the functional properties of nicotinic and muscarinic acetylcholine receptors. May regulate keratinocytes proliferation, differentiation and apoptosis. In vitro moderately inhibits ACh-evoked currents of alpha-3:beta-2-containing nAChRs and strongly these of alpha-4:beta-2-containing nAChRs, modulates alpha-7-containing nAChRs, and inhibits nicotine-induced signaling probably implicating alpha-3:beta-4-containing nAChRs. Proposed to act on alpha-3:beta-2 and alpha-7 nAChRs in an orthosteric, and on mAChRs, such as CHRM1 and CHRM3, in an allosteric manner. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Secreted LY6/PLAUR domain-containing protein 2; Secreted Ly-6/uPAR-related protein 2 |
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| Gene, Accession, CAS # | SLURP2, UniProt: P0DP57 |
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| Catalog # | RPC25512 |
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| Order / More Info | Recombinant Human Secreted Ly-6/uPAR domain-containing protein 2 (SLURP2) from BIOMATIK |
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| Product Specific References | n/a |
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