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Antigenic Specificity | PD-1 (CD279) |
Clone | RM309 |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry: 1:200-1:500, Western Blot: 1:100-1:200 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PD-1 (CD279) Monoclonal Antibody (RM309). CD279 encoded protein is a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 5133; Uniprot: Q15116 |
Catalog # | MA5-27899 |
Price | |
Order / More Info | PD-1 (CD279) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |