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| Product Name | AU RNA Binding Protein/enoyl-CoA Hydratase (AUH) (AA 68-339) protein (His tag) |
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| Description | Mitochondrial methylglutaconyl-CoA hydratase (AUH) is involved in the AA degradation pathway by catalyzing the conversion of 3-methylglutaconyl-CoA to 3-hydroxy-3-methylglutaryl-CoA and water. AUH Human is expressed as a single mRNA species of 1.8 kb, and translated as a 40 kDa precursor protein which is consequently processed to a 32 kDa mature form. AUH has a very low enoyl-CoA hydratase activity. The AUH protein binds to the AU-rich element (ARE), which is a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. AU-rich elements are involved in directing RNA to rapid degradation and deadenylation. In addition, AUH is homologous to enol-CoA hydratase, which is an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is therefore a bifunctional chimera between RNA binding and metabolic enzyme activity Synonyms: Methylglutaconyl-CoA hydratase, mitochondrial, AU-specific RNA-binding enoyl-CoA hydratase, AU-binding protein/enoyl-CoA hydratase, AUH |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5033405N08Rik|wu:fb81b10|zgc:101057|C77140|W91705 |
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| Gene, Accession, CAS # | Gene ID: 549 |
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| Catalog # | ABIN805350 |
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| Order / More Info | AU RNA Binding Protein/enoyl-CoA Hydratase (AUH) (AA 68-339) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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