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Product Name | EPO Alpha protein |
Description | EPO Alpha protein.The glycoprotein hormone erythropoietin (EPO) is anessential viability and growth factor for the erythrocyticprogenitors and is mainly produced in the kidneys. EPOand its receptor are also expressed in many other tissues,including brain, spinal cord, retina and testis.The presence of a blood barrier suggests that EPO playsa local role in these organs.EPO signalling involves tyrosine phosphorylation of thehomodimeric EPO receptor and subsequent activation ofintracellular anti-apoptotic proteins, kinases and transcription factors. Lack of EPO leads to anemia. Treatmentwith recombinant human EPO is efficient and safe inimproving the management of the anemia associated withchronic renal failure.Recombinant Human Erythropoietin is producedin Chinese hamster ovary (CHO) cells by recombinantDNA technology is a single, polypeptide chain containing165 amino acids and having a predicted molecular massof 21 kDa and apparent glycosylated molecular mass of30.4 kDa.EPO is purified by proprietary chromatographictechniques. Purity 95% pure by SDS-PAGE and RP-HPLC |
Size | 50 ug |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | UniProt: P01588 |
Catalog # | orb97749 |
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Order / More Info | EPO Alpha protein from BIORBYT LTD. |
Product Specific References | n/a |
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