| 产品详情 |
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| Antigenic Specificity | BAG3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:50-1:200, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BAG3 Polyclonal Antibody. BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
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| Immunogen | n/a |
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| Other Names | BAG-3, BIS, CAIR-1, BAG family molecular chaperone regulator 3, BAG-family molecular chaperone regulator-3, BCL2-binding athanogene 3, bcl-2-associated athanogene 3, bcl-2-binding protein Bis, docking protein CAIR-1 |
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| Gene, Accession # | Entrez: 9531; Uniprot: O95817 |
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| Catalog # | PA5-54239 |
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| Price | |
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| Order / More Info | BAG3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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