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| Antigenic Specificity | BAG3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:100-1:500, Immunoprecipitation: 2-5 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BAG3 Polyclonal Antibody. BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
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| Immunogen | n/a |
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| Other Names | BAG3; BCL2-associated athanogene 3; BIS; BAG-3; CAIR-1; MGC104307; DKFZp434E0610; Bcl-2-binding protein; docking protein CAIR-1; BCL2-binding athanogene 3; BAG-family molecular chaperone regulator-3 |
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| Gene, Accession # | Entrez: 9531; Uniprot: O95817 |
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| Catalog # | A302-806A |
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| Price | |
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| Order / More Info | BAG3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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