产品详情 |
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Antigenic Specificity | CD321 (F11R) |
Clone | H202-106 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD321 (F11R) Monoclonal Antibody (H202-106). JAM-A (CD321, F11R) seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. F11R also plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier; ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration; is involved in platelet activation. Further, F11R acts as a receptor for Mammalian reovirus sigma-1. Diseases associated with F11R include Mental Retardation, Enteropathy, Deafness, Peripheral Neuropathy, Ichthyosis, An |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 16456; Uniprot: O88792 |
Catalog # | MA5-28179 |
Price | |
Order / More Info | CD321 (F11R) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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