| 产品详情 |
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| Antigenic Specificity | p130Cas |
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| Clone | CAS-14 (35B-1A4) |
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| Host Species | Mouse |
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| Reactive Species | human, rat |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1-2 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p130Cas Monoclonal Antibody (CAS-14 (35B-1A4)). The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich region p130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation. |
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| Immunogen | n/a |
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| Other Names | Cas scaffolding protein family member 1, Crk-associated substrate p130Cas,breast cancer anti-estrogen resistance protein 1 |
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| Gene, Accession # | Entrez: 25414, 9564; Uniprot: P56945, Q63767 |
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| Catalog # | MA5-14276 |
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| Price | |
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| Order / More Info | p130Cas Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 14997499, 19680458, 22476538 |
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