Edit |   |
Antigenic Specificity | PCBP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Western Blot: 1:100 - 1:250 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PCBP1 Polyclonal Antibody. This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular polydomains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational cont |
Immunogen | n/a |
Other Names | Poly(rC) binding protein 1; HNRPE1; HNRPX; hnRNP-E1; hnRNP-X |
Gene, Accession # | Entrez: 5093; Uniprot: Q15365 |
Catalog # | PA5-66993 |
Price | |
Order / More Info | PCBP1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |