产品详情 |
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Antigenic Specificity | MANF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 20 µL |
Concentration | n/a |
Applications | Western Blot: 1:1,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MANF Polyclonal Antibody. The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of a specific mutation changing the previously numbered codon 50 from ATG to AGG, or deletion of that codon, has been reported in a variety of solid tumors. With the protein size correction, this codon is now identified as the initiation codon. |
Immunogen | n/a |
Other Names | ARMET; arginine-rich, mutated in early stage tumors; ARP; MANF; MGC142148; MGC142150; arginine-rich protein |
Gene, Accession # | Entrez: 74840, 7873; Uniprot: P55145, Q9CXI5 |
Catalog # | A305-572A-T |
Price | |
Order / More Info | MANF Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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