| 产品详情 |
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| Antigenic Specificity | Arfaptin 1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunofluorescence: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Arfaptin 1 Polyclonal Antibody. Arfaptin 1 is an ARF binding protein that inhibits PLD activation, vesicular trafficking and secretion. In the present report, we show that arfaptin 1 interacts with 'high speed' membranes independently of ARF. However, addition of myristoylated ARF3 (myrARF3) increases the association of arfaptin 1 with the membranes, suggesting that arfaptin 1 and ARF form a complex on the Golgi. Utilizing several deletion mutants of arfaptin 1 it is shown that the association of arfaptin 1 with myrARF3 is mediated via two binding sites on arfaptin 1. These two domains are needed for arfaptin 1 inhibition of PLD activation by myrARF3 in vitro. |
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| Immunogen | n/a |
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| Other Names | Arfaptin-1, ADP-ribosylation factor-interacting protein 1, ARFIP1, Arfaptin1 |
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| Gene, Accession # | Entrez: 27236, 60382, 99889; Uniprot: P53367, Q9JHU5 |
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| Catalog # | PA5-36427 |
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| Price | |
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| Order / More Info | Arfaptin 1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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