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Antigenic Specificity | CD45.1 |
Clone | A20 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2a, kappa |
Format | biotin conjugate |
Size | 500 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.25 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45.1 Monoclonal Antibody (A20), Biotin, eBioscience™. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depen |
Immunogen | n/a |
Other Names | CD45, L-CA, Lca, RT7, T200 |
Gene, Accession # | Entrez: 19264; Uniprot: P06800 |
Catalog # | 13-0453-85 |
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Order / More Info | CD45.1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 15520244, 16278309, 16314436, 16332975, 17438277, 18832997, 19373228, 19748987, 20074534, 20525889, 20978352, 21307296, 21449942, 22131331, 22444632, 22778389, 22802417, 23212524, 23334789, 23741395, 24846540, 25225459, 25407678, 25981357, 26374999, 26647186, 27030824, 27453007, 27523608, 28487311 |
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