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Antigenic Specificity | CD45.1 |
Clone | A20 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2a, kappa |
Format | phycoerythrin (PE) conjugate |
Size | 200 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.5 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45.1 Monoclonal Antibody (A20), PE, eBioscience™. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends o |
Immunogen | n/a |
Other Names | CD45, L-CA, Lca, RT7, T200 |
Gene, Accession # | Entrez: 19264; Uniprot: P06800 |
Catalog # | 12-0453-83 |
Price | |
Order / More Info | CD45.1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 14679176, 17664294, 18004562, 18689546, 19109157, 19360122, 20479114, 20660711, 21297009, 21677778, 21906575, 22124124, 22248039, 22251480, 22475534, 22531927, 23263555, 23334789, 23389440, 23511628, 23567932, 24025767, 24056746, 24279871, 24334453, 25079315, 25225459, 25326802, 25337791, 25981357, 26456157, 26457757, 26627460, 26647186, 26657857, 26989084, 27030824, 27111842, 27396339, 27453007, 27523608, 27810923, 27941791, 28241143, 28330582, 28486541, 28487311, 28875933, 29386580 |
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