产品详情 |
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Antigenic Specificity | CD45.1 |
Clone | A20 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2a, kappa |
Format | PE-Cyanine7 conjugate |
Size | 50 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.5 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45.1 Monoclonal Antibody (A20), PE-Cyanine7, eBioscience™. CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression |
Immunogen | n/a |
Other Names | CD45, L-CA, Lca, RT7, T200 |
Gene, Accession # | Entrez: 19264; Uniprot: P06800 |
Catalog # | 25-0453-81 |
Price | |
Order / More Info | CD45.1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 16127161, 16260487, 17090683, 17911583, 18689546, 18768876, 18802060, 19273628, 19494259, 20357087, 21078889, 21300983, 21765014, 21906575, 21931869, 22079990, 22504926, 22778389, 23334789, 23417922, 23736699, 23813389, 23893082, 23924635, 24226767, 24470501, 24614106, 24699869, 24747640, 25079788, 25225459, 25326802, 25411201, 25599133, 25634742, 25841547, 25917102, 25981357, 26147567, 26390038, 26551682, 26583087, 26608918, 26647186, 26832402, 26851220, 27030824, 27111842, 27257599, 27428079, 27453007, 27518241, 27523608, 28024152, 28191887, 28241143, 28270614, 28290453, 28351984, 28407484, 28487311, 29370156 |
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