产品详情 |
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Antigenic Specificity | P23 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:2,000-1:10,000, Immunoprecipitation: 2-10 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | P23 Polyclonal Antibody. Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448). |
Immunogen | n/a |
Other Names | Co chaperone p23, Hsp90 co chaperone, Progesterone receptor complex, Sid 3177, TEBP, Telomerase binding protein p23 |
Gene, Accession # | Entrez: 10728, 56351; Uniprot: Q15185, Q9R0Q7 |
Catalog # | A304-499A |
Price | |
Order / More Info | P23 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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