产品详情 |
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Antigenic Specificity | AKR1C4 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunohistochemistry: 2-4 µg/mL, peptide-ELISA: 1:4000, Western Blot: 0.1-0.3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AKR1C4 Polyclonal Antibody. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. |
Immunogen | n/a |
Other Names | AKR1C4; aldo-keto reductase family 1, member C4; HGNC:387; 3-alpha-HSD; C11; CDR; CHDR; DD4; HAKRA; MGC22581; 3-alpha hydroxysteroid dehydrogenase, type I ; 3 alpha-hydroxysteroid dehydrogenase/dihydrodiol dehydrogenase 4; 3-alpha-hydroxysteroid dehydrogenase variant; aldo-keto reductase family 1, member C4; chlordecone reductase; dihydrodiol dehydrogenase 4; dihydrodiol dehydrogenase isozyme DD4; type I 3-alpha-hydroxysteroid dehydrogenase; |
Gene, Accession # | Entrez: 1109; Uniprot: P17516 |
Catalog # | PA5-18511 |
Price | |
Order / More Info | AKR1C4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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