| 产品详情 |
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| Antigenic Specificity | Ku70 |
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| Clone | N3H10 |
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| Host Species | Mouse |
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| Reactive Species | hamster, human, mouse, nonhuman primate, Xenopus laevis |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | ChIP assay: 2 µg/10^6 cells, Flow Cytometry: 0.25 µg/test, Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50 - 1:200, Immunohistochemistry (Paraffin): 1:200-1:400, Immunoprecipitation: 2 µg/mL, Western Blot: 0.25-0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Ku70 Monoclonal Antibody (N3H10). The Ku autoantigen is a heterodimer of 70kDa (p70) and ~80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis. |
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| Immunogen | n/a |
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| Other Names | 5'-dRP lyase Ku70, 5'-deoxyribose-5-phosphate lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, ATP-dependent DNA helicase II, 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, DNA repair protein XRCC6, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa,X-ray repair cross-complementing protein 6, lupus Ku autoantigen protein p70, thyroid autoantigen 70kD (Ku antigen), thyroid |
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| Gene, Accession # | Entrez: 100770214, 14375, 2547, 398357; Uniprot: P12956, P23475 |
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| Catalog # | MA5-13110 |
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| Price | |
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| Order / More Info | Ku70 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10400681, 10945984, 11474179, 11844796, 12527196, 12547193, 12917393, 15498778, 15520013, 16014360, 16179499, 16537533, 17631504, 18377429, 18463164, 19715578, 19759212, 19833092, 20424183, 21283680, 21679440, 22893792, 23337116, 23591994, 23704914, 23775790, 24635384, 25582113, 25811803, 25947322, 26234763, 26337656, 27057999, 27111890, 28317875 |
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