产品详情 |
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Antigenic Specificity | CD38 |
Clone | HIT2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: Assay Dependent, Immunohistochemistry (Frozen): Assay Dependent, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD38 Monoclonal Antibody (HIT2). CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, ma |
Immunogen | n/a |
Other Names | T10, ADP-ribosyl cyclase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase, CD38 antigen p45, NAD+ nucleosidase, cADPr hydrolase 1, cyclic ADP-ribose hydrolase 1 |
Gene, Accession # | Entrez: 952; Uniprot: P28907 |
Catalog # | MA1-19316 |
Price | |
Order / More Info | CD38 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 10554819, 12139742, 12239170, 12388703, 15597326, 16480521, 16531260, 16603627, 16828866, 16918701, 17132718, 17252012, 18512812, 19180077, 26724942, 27059652, 27379802, 27612555, 27941243, 28084312, 9489644, 9649209 |
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