| 产品详情 |
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| Antigenic Specificity | Optineurin |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-5 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Optineurin Polyclonal Antibody. This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. |
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| Immunogen | n/a |
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| Other Names | ALS12, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP, E3-14.7K-interacting protein, FIP-2, HIP-7, Huntingtin interacting protein L, huntingtin yeast partner L, huntingtin-interacting protein 7, huntingtin-interacting protein L, nemo-related protein, optic neuropathy-inducing protein, transcription factor IIIA-interac, Uban |
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| Gene, Accession # | Entrez: 10133; Uniprot: Q96CV9 |
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| Catalog # | A301-831A |
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| Price | |
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| Order / More Info | Optineurin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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