| 产品详情 |
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| Antigenic Specificity | Bub3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | Drosophila |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bub3 Polyclonal Antibody. The mitotic checkpoint protein Bub3 is involved with the essential spindle checkpoint pathway which operates during early embryogenesis. Bub3 is important during G2 and early mitosis stages, permitting entry into mitosis depending upon the assembly state of microtubules, thus preventing premature sister chromatid separation, mis-segregation and aneuploidy. Bub3 contains four WD repeat domains and is required for the kinetochore localization of Bub1, a related kinase that is necessary for spindle assembly checkpoint function. Bub1 is able to autophosphorylate and can catalyze the phosphorylation of Bub3. Both Bub1 and Bub3 are mutually dependent for function. Altered Bub expression levels may significantly impair mi |
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| Immunogen | n/a |
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| Other Names | BUB3 budding uninhibited by benzimidazoles 3 homolog; OTTHUMP00000020682; budding uninhibited by benomyl; mitotic checkpoint component; mitotic checkpoint protein BUB3 |
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| Gene, Accession # | Entrez: 43490 |
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| Catalog # | PA5-72174 |
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| Price | |
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| Order / More Info | Bub3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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