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| Product Name | Phosphodiesterase 12 (PDE12) peptide |
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| Description | 2'-PDE is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. 2'-PDE also cleaves 3',5'-phosphodiester bond of oligoadenylates. 2'-PDE play a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | 2'-PDE|E430028B21Rik|LRRGT00074|RGD1310975 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN937120 |
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| Price | |
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| Order / More Info | Phosphodiesterase 12 (PDE12) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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| 产品资料 |
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