产品详情 |
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Antigenic Specificity | CD45.2 |
Clone | 104 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2a, kappa |
Format | eFluor 506 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.25 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45.2 Monoclonal Antibody (104), eFluor 506, eBioscience™. CD45.2 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45.2 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45.2 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression |
Immunogen | n/a |
Other Names | B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, CD45 antigen, T200 glycoprotein, T200 leukocyte common antigen, protein tyrosine phosphatase, receptor type, c polypeptide, receptor-type tyrosine-protein phosphatase C, PTPRC |
Gene, Accession # | Entrez: 19264; Uniprot: P06800 |
Catalog # | 69-0454-82 |
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Order / More Info | CD45.2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 23334789, 23396050, 23644504, 23720750, 25225459, 25259859, 25858253, 26137411, 27453007, 27523608, 27716507, 28194010, 28355185, 28355561, 28363640, 28487311, 29312584 |
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