产品详情 |
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Antigenic Specificity | DIABLO |
Clone | SMAC 17 1-87 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 1:20-1:200, Immunofluorescence: 1:20-1:200, Immunohistochemistry (Paraffin): 1:20-1:200, Immunoprecipitation: Assay dependent, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DIABLO Monoclonal Antibody (SMAC 17 1-87). Second mitochondria-derived activator of caspase/direct inhibitor of apoptosis-binding protein with low pI (Smac/DIABLO) is a protein that is released from the mitochondria into the cytosol as a response to apoptic stimuli. It enables apoptosis by neutralizing the inhibitory effect of inhibitor of apoptosis proteins (IAP's). Smac/DIABLO has also been found to play a key role in regulating the sensitization of cancer cells to apoptosis (both immune and drug-induced). |
Immunogen | n/a |
Other Names | SMAC, Second mitochondria-derived activator of caspase, Direct IAP Binding Protein with Low pI |
Gene, Accession # | Entrez: 288753, 56616, 66593; Uniprot: Q9JIQ3, Q9NR28 |
Catalog # | MA1-936 |
Price | |
Order / More Info | DIABLO Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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