| 产品详情 |
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| Antigenic Specificity | Perforin |
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| Clone | eBioOMAK-D |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Perforin Monoclonal Antibody (eBioOMAK-D), eBioscience™. Perforin is one of the major cytolytic proteins of cytolytic granules. Perforin is a cytolytic mediator and is stored in and released by cytoplasmic granules. Moreover, perforin is involved in immune defense against tumors and virus infections as mediated by cytotoxic lymphocytes. Perforin is a 555 amino acid protein with a 21 amino acid signal peptide, and has a molecular weight of 70 to 75 kD. Perforin is a pore forming protein with a mechanism of transmembrane channel formation similar to C9, and homology between perforin and C9 have been demonstrated. Studies show that perforin is expressed only in killer cell lines and not in helper T lymphocytes or other tumor cells tested |
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| Immunogen | n/a |
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| Other Names | cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; lymphocyte pore-forming protein; perforin 1 (pore forming protein); perforin-1; PFN1; PFP; RP11-710A11.3 |
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| Gene, Accession # | Entrez: 18646; Uniprot: P10820 |
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| Catalog # | 14-9392-82 |
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| Price | |
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| Order / More Info | Perforin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 19454713, 19889780, 20130237, 20156973, 21614029, 23565245, 25337993, 26277898, 28382040, 28504276, 28894104 |
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