产品详情 |
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Antigenic Specificity | PERK |
Clone | 5G5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1/500 - 1/2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PERK Monoclonal Antibody (5G5). The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 , leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum , where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. |
Immunogen | n/a |
Other Names | PEK; WRS; PERK; EIF2AK3 |
Gene, Accession # | Entrez: 9451; Uniprot: Q9NZJ5 |
Catalog # | MA5-15705 |
Price | |
Order / More Info | PERK Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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