产品详情 |
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Antigenic Specificity | CD263 (TRAIL-R3) |
Clone | TRAIL-R3-02 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 100 ug |
Concentration | n/a |
Applications | Flow Cytometry: 3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD263 (TRAIL-R3) Monoclonal Antibody (TRAIL-R3-02), PE. TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5). |
Immunogen | n/a |
Other Names | CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID |
Gene, Accession # | Entrez: 8794; Uniprot: O14798 |
Catalog # | MA1-10162 |
Price | |
Order / More Info | CD263 (TRAIL-R3) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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