| 产品详情 |
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| Antigenic Specificity | CD263 (TRAIL-R3) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 20 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD263 (TRAIL-R3) Polyclonal Antibody. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts are expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis |
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| Immunogen | n/a |
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| Other Names | CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID |
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| Gene, Accession # | Entrez: 8794; Uniprot: O14798 |
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| Catalog # | PA5-19959 |
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| Price | |
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| Order / More Info | CD263 (TRAIL-R3) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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