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Antigenic Specificity | CD263 (TRAIL-R3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: Assay dependent, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD263 (TRAIL-R3) Polyclonal Antibody. DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis. |
Immunogen | n/a |
Other Names | CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID |
Gene, Accession # | Entrez: 246775, 8743, 8794; Uniprot: O14798, P50591 |
Catalog # | PA1-956 |
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Order / More Info | CD263 (TRAIL-R3) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 15623796 |
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