| 产品详情 |
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| Antigenic Specificity | CD11b |
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| Clone | M1/70.15 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2b |
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| Format | biotin conjugate |
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| Size | 1 mL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD11b Monoclonal Antibody (M1/70.15), Biotin. CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, |
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| Immunogen | n/a |
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| Other Names | CD11B, CR3A, MAC-1, MAC1A, MGC117044, MO1A, SLEB6, Integrin alpha M |
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| Gene, Accession # | Entrez: 16409; Uniprot: P05555 |
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| Catalog # | RM2815 |
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| Price | |
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| Order / More Info | CD11b Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11166461, 11466351, 11489992, 12813443, 15784728, 15870020, 19234155, 19652197, 21060663, 9067539 |
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