| 产品详情 |
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| Antigenic Specificity | MSRA |
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| Clone | 5B5 |
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| Host Species | Mouse |
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| Reactive Species | human, rat |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): Assay dependent, Immunoprecipitation: 1-2 µL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MSRA Monoclonal Antibody (5B5). Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and a 1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimer's disease in mammals. |
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| Immunogen | n/a |
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| Other Names | cytosolic methionine-S-sulfoxide reductase |
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| Gene, Accession # | Entrez: 29447, 4482; Uniprot: Q923M1, Q9UJ68 |
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| Catalog # | LF-MA0084 |
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| Price | |
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| Order / More Info | MSRA Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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