| 产品详情 |
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| Antigenic Specificity | PTP1B |
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| Clone | OTI1D10 |
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| Host Species | Mouse |
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| Reactive Species | canine, human, nonhuman primate |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PTP1B Monoclonal Antibody (OTI1D10). The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin |
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| Immunogen | n/a |
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| Other Names | PTP1B, protein tyrosine phosphatase 1B, protein tyrosine phosphatase, placental, protein-tyrosine phosphatase 1B, tyrosine-protein phosphatase non-receptor type 1 |
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| Gene, Accession # | Entrez: 477263, 5770, 702016; Uniprot: P18031 |
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| Catalog # | MA5-25642 |
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| Price | |
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| Order / More Info | PTP1B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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