产品详情 |
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Antigenic Specificity | Syndecan 4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: Assay Dependent, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Syndecan 4 Polyclonal Antibody. Syndecan-4 is a transmembrane (type I) heparan sulfate proteoglycan containing 198 amino acids and belonging to the syndecan proteoglycan family. Syndecan-4 functions as a receptor or coreceptor in intracellular signaling. Initially, Syndecan-4 was isolated as ryudocan, from rat endothelial cells, and from human epithelial and fibroblastic cells, as amphiglycan. The syndecan heparan sulfate chains of Syndecan-4 binds to HIV-1 gp120 and thus functions as trans HIV receptors. This cell surface proteoglycan usually exists as a homodimer that interacts with CDCP1, with GIPC PDZ domain and with NUDT16L1/SDOS. Reports suggest that Syndecan-4 is often upregulated in skin dermis after wounding, thus playing an import |
Immunogen | n/a |
Other Names | SYND4, amphiglycan, ryudocan amphiglycan, ryudocan core protein, syndecan 4 (amphiglycan, ryudocan), syndecan proteoglycan 4, syndecan-4 |
Gene, Accession # | Entrez: 6385; Uniprot: P31431 |
Catalog # | 36-3100 |
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Order / More Info | Syndecan 4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 15371538, 19401393, 19812150, 24357671 |
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