产品详情 |
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Antigenic Specificity | TTYH2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 2.5 µg/mL, Immunofluorescence: 2.5 µg/mL, Immunohistochemistry: 2.5 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TTYH2 Polyclonal Antibody. TTYH2 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH2 is a Ca2+-activated large conductance chloride (Cl-) channel and may play a role in kidney tumorigenesis. It is also upregulated in colon carcinoma and is thought to play a role in cell proliferation and call aggregation, suggesting that TTYH2 may play a role in regulating both proliferation and metastatic potentials of colorectal cancer. The ubiquitin-protein ligase Nedd4-2 binds to and ubiquitinates TTYH2, thereby regulating its cell surface expression and total cellular levels. |
Immunogen | n/a |
Other Names | TTYH2, Tweety homolog 2 |
Gene, Accession # | Entrez: 117160, 287803, 94015; Uniprot: Q3TH73, Q9BSA4 |
Catalog # | PA5-34395 |
Price | |
Order / More Info | TTYH2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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