产品详情 |
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Antigenic Specificity | BANF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:50-1:200 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BANF1 Polyclonal Antibody. Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA. BANF1 also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1. It is also a host cell component of retroviral pre-integration complexes (PICs), including that of HIV. BANF1 will bind to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix. In addition to being a host cell component of the PIC, it is thought that BANF1 is also present at low levels in incoming virions, and thus might contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix as well as DNA. |
Immunogen | n/a |
Other Names | BAF, BCRP1, D14S1460, NGPS; barrier-to-autointegration factor; breakpoint cluster region protein 1 |
Gene, Accession # | Entrez: 8815; Uniprot: O75531 |
Catalog # | PA5-58710 |
Price | |
Order / More Info | BANF1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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