产品详情 |
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Antigenic Specificity | HOXB4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, feline, human, mouse, nonhuman primate, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 1-3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HOXB4 Polyclonal Antibody. HOX homeobox genes play a role both in the early stem cell function as well as in later stages of hematopoietic differentiation. HOXB4, specifically, is a homeotic selector gene implicated in self-renewal of definitive HSCs. Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induced a switch to the definitive HSC phenotype. Activation of WNT signaling in HSCs induced increased expression of HOXB4. Perturbations of HOX gene expression can cause leukemia. |
Immunogen | n/a |
Other Names | HOX-2.6, HOX2, HOX2F, homeo box 2F, homeo box B4, homeobox protein Hox-2.6, homeobox protein Hox-2F, homeobox protein Hox-B4 |
Gene, Accession # | Entrez: 101096120, 15412, 3214, 497988, 768240; Uniprot: P10284, P17483, Q08DG5 |
Catalog # | PA5-23366 |
Price | |
Order / More Info | HOXB4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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