Edit |   |
Antigenic Specificity | KHDRBS3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Western Blot: 1:100 - 1:250 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KHDRBS3 Polyclonal Antibody. As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression. |
Immunogen | n/a |
Other Names | KH domain containing; RNA binding; signal transduction associated 3; Etle; SALP; SLM2; SLM-2; TSTAR; T-STAR; etoile |
Gene, Accession # | Entrez: 10656; Uniprot: O75525 |
Catalog # | PA5-64874 |
Price | |
Order / More Info | KHDRBS3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |