| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | BAP1 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | lyophilized |
|---|
| Applications | ELISA: Assay-dependent, Western Blot: 0.5 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | BAP1 Polyclonal Antibody. BRCA1-associated protein-1,' or BAP1 interacts with the RING finger domain of BRCA1. The N-terminal 240 amino acids of the predicted 729-amino acid human protein show homology to ubiquitin C-terminal hydrolases (UCHs), thiol proteases that catalyze proteolytic processing of ubiquitin. In addition, BAP1 contains an acidic region, a highly charged C-terminal region, and 2 putative nuclear localization signals. BAP1 and BRCA1 associate in vivo and have overlapping subnuclear localization patterns. BAP1 enhances BRCA1-mediated inhibition of breast cancer cell growth. Northern blot analysis indicates that BAP1 is expressed as a 4-kb mRNA in all human tissues tested, with A 4.8-kb transcript expressed exclusively in test |
|---|
| Immunogen | n/a |
|---|
| Other Names | Ubiquitin carboxyl-terminal hydrolase BAP1, BRCA1-associated protein 1, Cerebral protein 6, BAP1, KIAA0272, hucep-6 |
|---|
| Gene, Accession # | Entrez: 104416, 306257, 8314; Uniprot: D3ZHS6, Q92560, Q99PU7 |
|---|
| Catalog # | PA5-78856 |
|---|
| Price | |
|---|
| Order / More Info | BAP1 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|