| 产品详情 |
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| Antigenic Specificity | MINT3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MINT3 Polyclonal Antibody. Amyloid beta precursor protein ( beta APP) is a major constituent of the amyloid deposits in patients with Alzheimer's disease. The amyloid beta precursor is known to interact with several proteins, including the G heterotrimetric protein, APP-BP1, and X11. The neuronal, transmembrane protein X11 is known to bind to the amyloid beta precurser protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular beta APP and slowing beta APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of beta APP. Multiple splice varitents of X11 have been identified, including X11 alpha, beta and gamma (also known as Mint 1, 2 and 3, respectively). |
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| Immunogen | n/a |
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| Other Names | X11 like 2 protein 2, X11gamma, X11L2, APBA3, lin 10, MGC:15815, Mint 3 |
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| Gene, Accession # | Entrez: 9546; Uniprot: O96018 |
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| Catalog # | PA5-39019 |
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| Price | |
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| Order / More Info | MINT3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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