产品详情 |
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Antigenic Specificity | Mist1 |
Clone | 6E8/A12/C11P1 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunohistochemistry (Frozen): Assay Dependent, Immunohistochemistry (Paraffin): Assay Dependent, Western Blot: 1:100-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mist1 Monoclonal Antibody (6E8/A12/C11P1). Mist 1 plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. This protein also negatively regulates bHLH-mediated transcription through an N-terminal repressor domain, and serves as a key regulator of acinar cell function, stability, and identity. Mist 1 is also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport, and may function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. |
Immunogen | n/a |
Other Names | BHLHB8, MIST1 |
Gene, Accession # | Entrez: 168620, 17341; Uniprot: Q7RTS1, Q9QYC3 |
Catalog # | MA1-517 |
Price | |
Order / More Info | Mist1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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