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Antigenic Specificity | Nucleolin |
Clone | ZN004 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2b, kappa |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 5-10 µg/mL, Immunofluorescence: 5-10 µg/mL, Western Blot: 1-3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nucleolin Monoclonal Antibody (ZN004). Nucleolin, which is identical to human DNA helicase IV, is a major nucleolar phosphoprotein which is associated with preribosomal RNA and is implicated in the early stage of preribosomal RNP assembly and processing. This 100 kDa protein has three major domains: a N-terminal domain comprised of long acidic stretches interspersed with basic repeats, similar to the structure of a high mobility group-type protein, a central domain that contains four RNA binding elements, a C-terminal domain approximately 85 amino acids long that is rich in glycine, arginine, and phenylalanine residues. Nucleolin fluctuates in parallel to DNA synthesis; intact 100 kDa protein is the major species in actively dividing cells, |
Immunogen | n/a |
Other Names | C23, FLJ45706, FLJ59041 |
Gene, Accession # | Entrez: 17975, 4691; Uniprot: P09405, P19338 |
Catalog # | 39-6400 |
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Order / More Info | Nucleolin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 19188445, 19593743, 20873772, 21258971, 22918947, 24743236, 25580447, 26359175, 26764008, 27672210 |
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