| 产品详情 |
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| Product Name | Neurotensin (8-13) |
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| Description | Purity >95%. Neurotensin (8-13) is the smallest active fragment of neurotensin. Neurotensin(8-13) binds to the same sites as neurotensin. However;in the human brain;neurotensin(8-13) has a higher affinity for these sites than neurotensin does. The rapid degradation of neurotensin (NT) limits its clinical use in cancer imaging and therapy. Neurotensin(8-13) pseudopeptide;NT-VIII;was developed to sidestep this problem. Some changes were introduced to the sequence of neurotensin(8-13) to stabilize the molecule against enzymatic degradation: Arg8 is now N-methylated;and Lys and Tle have replaced Arg9 and Ile12;respectively. These have stabilized the molecule against enzymatic degradation without affecting its binding properties. Moreover;the increase in stability has enhanced tumor uptake;making this derivative a promising candidate for clinical use. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Arg-Arg-Pro-Tyr-Ile-Leu, NT(8-13) |
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| Gene, Accession, CAS # | CAS: 60482-95-3 |
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| Catalog # | LS-H4670 |
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| Order / More Info | Neurotensin (8-13) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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