| 产品详情 |
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| Antigenic Specificity | Phospho-HNF4A (Ser313) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-HNF4A (Ser313) Polyclonal Antibody. Hepatocyte nuclear factor 4 alpha (HNF4 alpha) is a transcription factor that belongs to the steroid hormone receptor superfamily and is enriched in liver. HNF4 alpha, in association with PGC-1 alpha, activates gluconeogenic genes such as phosphoenolpyruvate carboxykinase and glucose-6-phosphatase genes in fasted livers. Conditional knockout of the HNF4 alpha gene in the mouse liver destroys lipid homeostasis and leads to lipid accumulation in the liver and a reduction of serum cholesterol and triglyceride levels. Mutations in HNF4 alpha have been linked to maturity-onset diabetes of the young (MODY). |
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| Immunogen | n/a |
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| Other Names | Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, TCF-14, Transcription factor HNF-4, HNF4A, HNF4, NR2A1, TCF14 |
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| Gene, Accession # | Entrez: 15378, 25735, 3172; Uniprot: P22449, P41235, P49698 |
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| Catalog # | PA5-39695 |
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| Price | |
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| Order / More Info | Phospho-HNF4A (Ser313) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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