| 产品详情 |
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| Antigenic Specificity | Phospho-HSF1 (Ser121) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-HSF1 (Ser121) Polyclonal Antibody. Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level. HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway. |
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| Immunogen | n/a |
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| Other Names | Heat shock factor 1, Heat shock factor protein 1, Heat shock transcription factor 1, HSF 1, hsf1, HSF1, HSTF 1, HSTF1 |
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| Gene, Accession # | Entrez: 15499, 3297; Uniprot: P38532, Q00613 |
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| Catalog # | PA5-39718 |
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| Price | |
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| Order / More Info | Phospho-HSF1 (Ser121) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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