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| Antigenic Specificity | Phospho-HSP27 (Ser85) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Immunocytochemistry: 15 -25 µg/mL, Immunofluorescence: 15-25 µg/mL, Immunohistochemistry (Paraffin): 1:100, Immunoprecipitation: 3 µg, Western Blot: 0.25-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-HSP27 (Ser85) Polyclonal Antibody. HSP27 also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins (HSP) produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSP's and mammalian a-crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. This work has led to the suggestion that HSP27 may be a useful marker in classifying various hormone sensitive tumors. |
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| Immunogen | n/a |
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| Other Names | Phospho-HSP 27; Heat shock protein beta-1; HspB1; HSP25; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27; Estrogen-regulated 24 kDa protein; 28 kDa heat shock protein; HSPB1; HSP27 |
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| Gene, Accession # | Entrez: 24471, 3315; Uniprot: P04792, P42930 |
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| Catalog # | PA1-005 |
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| Price | |
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| Order / More Info | Phospho-HSP27 (Ser85) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 21050276, 21632719 |
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