| 产品详情 |
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| Antigenic Specificity | Phospho-Huntingtin (Ser434) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunofluorescence: 1:100 - 1:200, Immunohistochemistry: 1:100 - 1:200, Western Blot: 1:250 - 1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-Huntingtin (Ser434) Polyclonal Antibody. Huntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. The huntingtin locus is large, spanning 180 kb and consisting of 67 exons. The huntingtin gene is widely expressed and is required for normal development. It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues. The larger transcript is approximately 13.7 kb and is expressed predominantly in adult and fetal brain whereas the |
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| Immunogen | n/a |
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| Other Names | Htt, Huntingtin, HD, IT15 |
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| Gene, Accession # | Entrez: 15194, 3064; Uniprot: P42858, P42859 |
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| Catalog # | PA1-088 |
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| Price | |
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| Order / More Info | Phospho-Huntingtin (Ser434) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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