产品详情 |
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Antigenic Specificity | Phospho-ICAM-3 (Ser518) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-ICAM-3 (Ser518) Polyclonal Antibody. CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is invol |
Immunogen | n/a |
Other Names | CD50, CDW50, ICAM-R, ICAM-3, intercellular adhesion molecule-3 |
Gene, Accession # | Entrez: 3385; Uniprot: P32942 |
Catalog # | PA5-38450 |
Price | |
Order / More Info | Phospho-ICAM-3 (Ser518) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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