产品详情 |
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Antigenic Specificity | Phospho-IGF1R beta (Tyr980) |
Clone | T.968.0 |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-IGF1R beta (Tyr980) Monoclonal Antibody (T.968.0). This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. |
Immunogen | n/a |
Other Names | IGF-I receptor; insulin-like growth factor I receptor; soluble IGF1R variant 1; soluble IGF1R variant 2 |
Gene, Accession # | Entrez: 16001, 25718, 3480; Uniprot: P08069, P24062, Q60751 |
Catalog # | MA5-14859 |
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Order / More Info | Phospho-IGF1R beta (Tyr980) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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