| 产品详情 |
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| Antigenic Specificity | Phospho-IkB alpha (Ser32) |
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| Clone | 6H4L6 |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-IkB alpha (Ser32) Antibody (6H4L6), ABfinity™ Rabbit Monoclonal. IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity. The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol. The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus. A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha. These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses. |
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| Immunogen | n/a |
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| Other Names | IKBA, MAD-3, NFKBI, I-kappa-B-alpha, IkappaBalpha, NF-kappa-B inhibitor alpha, ikB-alpha, major histocompatibility complex enhancer-binding protein MAD3, nuclear factor of kappa light chain gene enhancer in B-cells |
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| Gene, Accession # | Entrez: 4792; Uniprot: P25963 |
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| Catalog # | 701271 |
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| Price | |
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| Order / More Info | Phospho-IkB alpha (Ser32) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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