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| Antigenic Specificity | Phospho-IkB alpha (Ser32, Ser36) |
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| Clone | RILYB3R |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG2b, kappa |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 100 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 5 µL (0.125 µg)/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-IkB alpha (Ser32, Ser36) Monoclonal Antibody (RILYB3R), PE, eBioscience™. IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity. The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol. The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus. A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha. These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical s |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 18035, 4792; Uniprot: P25963, Q9Z1E3 |
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| Catalog # | 12-9035-42 |
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| Order / More Info | Phospho-IkB alpha (Ser32, Ser36) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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